Perbedaan titer imunoglobulin-g campak anak usia sekolah dasar yang obesitas dan tidak obesitas di SD Bromantakan kota Surakarta

Giri Moelyo, Annang (2007) Perbedaan titer imunoglobulin-g campak anak usia sekolah dasar yang obesitas dan tidak obesitas di SD Bromantakan kota Surakarta. Masters thesis, Universitas Sebelas Maret Surakarta .

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    Abstract

    Background: There is an increasing trend of measles incidence in elementary school children. Nutritional status influence measles antibody level. An obese child have measles immune status differ from a normal child. Objectives: To find out the differences of measles IgG in obese and non-obese elementary school children in SD Bromantakan Kota Surakarta. Methods: A cross sectional study was conducted from March to August, 2006 to elementary school children in SD Bromantakan Kecamatan Banjarsari Kota Surakarta. Obese children were selected antropometrically and fulfill inclusion and exclusion criteria, then matched by age and gender to non-obese groups. Laboratory examination (Measles IgG and hemoglobine) and interview to the parents were performed. Data were analyzed by SPSS 10.00 for Windows. Mean and proportion between two groups were performed for demography and measles virus contact characteristic Paired t-test were used to measles IgG titer between two groups. Age and gender were examined by chi square test. Univariate and multivariate analysis were performed to factors contributed in measles IgG titer, ie obese, hemoglobine level and frequency of measles virus contact. Results: The means of measles IgG titer in obese and non-obese groups were 2502,12+1834,71 and 2201,30+1467,72 mIU/ml, respectively, with mean difference 300,82 mIU/ml (p = 0,354; 95% CI (-1410,77)-(2012,42)). The means of hemoglobine level in obese and non-obese groups were 14,47+0,87 and 13,79+0,91 g/dl, respectively, with mean difference 0,68 g/dl (95%CI 0,01-1,35; p = 0,048). Univariate analysis for the measles titer were obesity 1,36 (0,29-6,36); hemoglobine level (>=14,05 g/dl) 1,36 (0,29- 6,36); and frequency of measles virus contact (more than once) 14 (1,39-141,49). In multivariate analysis, the relative risk for obesity, hemoglobine level (>=14,05 g/dl), and frequency of measles virus contact were 1,06 (0,17 – 6,42),g/dl); 1,51 (0,25 – 9,09); and 14,46 (1,38 – 151,67), respectively. Conclusion: Elementary children with obesity tend to have measles IgG titer mean higher than non-obese ones. The frequency of measles virus contact more than once increases the measles IgG titer. Keywords: measles IgG titer, obesity, elementary school children.

    Item Type: Thesis (Masters)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Pasca Sarjana > Magister
    Pasca Sarjana > Magister > Magister Kedokteran Keluarga
    Depositing User: Riza Umami Nur K
    Date Deposited: 25 Jul 2013 18:13
    Last Modified: 25 Jul 2013 18:13
    URI: https://eprints.uns.ac.id/id/eprint/9408

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