PENGARUH DIET UMBI SINGKONG (Manihot esculenta Crantz) TERHADAP STRUKTUR HISTOLOGIS EKSOKRIN PANKREAS TIKUS PUTIH (Rattus Norvegicus)

Suary, Adriani Netiasa (2010) PENGARUH DIET UMBI SINGKONG (Manihot esculenta Crantz) TERHADAP STRUKTUR HISTOLOGIS EKSOKRIN PANKREAS TIKUS PUTIH (Rattus Norvegicus). Other thesis, Universitas Sebelas Maret.

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    Abstract

    Objective: This reasearch aimed to discover whether or not there was an effect by Cassava (Manihot esculenta) on the histological structure of white rat’s (Rattus norvegicus) pancreas Methods: This research is laboratoric experimental with Post Test Only Control Group Design. It was conducted in the Histology Laboratory of Sebelas Maret University, Surakarta. The subjects of this research were 27 Wistar strain male white rats (Rattus norvegicus) aged twelve months and weiged between 150-200 grams. They were divided into three groups, each of which consisted of nine white rats. K was a control group which given standart diet. P1 was given 100% cassava ad libitum. P2 was given mixed standart diet and choped cassava with a comparison 1:1 ad libitum. This research was done on 6 weeks. For the diameter of acinus exocrine pancreas, data was analysed with One-Way Anova test and was continued with LSD Post Hoc Test and for the increasing of fibrotic tissue, data was analysed with Kruskal Wallis test and continued with Mann Whitney test using SPSS for Windows Release 17 program. The difference were stated significant if the p < 0,05. Results: This research showed the means of diameters of asinus pankreas exocrine. For control group (K) is 18,2625 µm, P1 is 10,7531 µm and P2 is 19,5507 µm. There were significant difference between K group and P1 group (p=0,000), K group and P2 group (p=0,036), P1 group and P2 group (p=0,000). For the increasing of fibrosis, there were significant difference between K group and P1 group (p=0,001), P1 group and P2 group (p=0,002) but there were not significant difference between K group and P2 group (p=0,609). Conclussion: Provision of cassava diet can affect the histological structure of the exocrine pancreas of white rats marked by the diferrences in average diameter of the acini and increasing of fibrotic tissue for each group compared with control group. Keyword : Pancreas – Cassava (Manihot esculenta) - Exocrine

    Item Type: Thesis (Other)
    Subjects: L Education > L Education (General)
    R Medicine > R Medicine (General)
    Divisions: Fakultas Kedokteran
    Fakultas Kedokteran > Pendidikan Kedokteran
    Depositing User: Andika Setiawan
    Date Deposited: 18 Jul 2013 17:04
    Last Modified: 18 Jul 2013 17:04
    URI: https://eprints.uns.ac.id/id/eprint/6356

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