Efek Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq.) terhadap Mortalitas Larva Aedes aegypti [L.]

ELVIRA A, AMALINA (2018) Efek Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq.) terhadap Mortalitas Larva Aedes aegypti [L.]. Other thesis, Universitas Sebelas Maret.

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    Abstract

    ABSTRAK Amalina Elvira Anggraini, G0014023, 2017. Efek Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq.) terhadap Larva Nyamuk Aedes aegypti [L.]. Skripsi. Fakultas Kedokteran, Universitas Sebelas Maret, Surakarta. Latar Belakang: Pemberantasan nyamuk Aedes aegypti [L.] yang merupakan vektor peyakit demam berdarah dengue, chikungunya, dan zika telah banyak dilakukan salah satunya dengan menggunakan temephos 1%. Namun, penggunaan temephos 1% ini telah menimbulkan resistensi di beberapa kota di Indonesia, khususnya Jawa Tengah. Oleh karena itu, perlu dilakukan penelitian untuk mencari larvasida alami salah satunya dengan daun dadap serep (Eryhtrina lithosperma Miq.) yang mengandung flavonoid, saponin, dan tanin. Penelitian ini bertujuan untuk melihat apakah ekstrak etanol daun dadap serep (Eryhtrina lithosperma Miq.) memiliki efek mortalitas terhadap larva nyamuk Aedes aegypti [L.]. Metode Penelitian: Jenis penelitian adalah quasi ekperimental laboratorium dengan rancangan post test only controlled group design. Obyek penelitian adalah larva Aedes aegypti [L.] yang dibagi menjadi 6 kelompok, masing-masing berisi 25 larva nyamuk dan dilakukan pengulangan 4 kali. Kelompok kontrol negatif menggunakan 100 ml akuades. Enam kelompok lainnya diberi ekstrak etanol daun dadap serep yang terdiri dari 0,3%; 0,5%; 0,7%; 0,9%; dan 1,1%. Pengamatan dilakukan dalam 24 jam kemudian dihitung jumlah larva nyamuk yang mati. Data diuji menggunakan Regresi Linear dan Regresi Probit. Hasil Penelitian: Uji Regresi Linear menunjukkan bahwa kenaikan ekstrak etanol daun Dadap Serep (Erythrina lithosperma Miq.) mempengaruhi kenaikan mortalitas larva Aedes aegypti [L.] berdasarkan rumus Y=0,024 + 0,956X. Nilai korelasi R sebesar 0,994 serta R2 sebesar 0,968 yang berarti persentase pengaruh variabel ekstrak etanol daun dadap serep terhadap mortalitas larva sebesar 96,8% dan sisanya 3,2% dipengaruhi variabel lain. Regresi Probit menunjukkan LC50 pada 0,492% dan LC99 pada 1,107%. Simpulan Penelitian: Ekstrak etanol daun dadap serep (Erythrina lithosperma Miq.) memiliki efek mortalitas terhadap larva Aedes aegypti [L.]. LC50 sebesar 0,492% dan LC99 sebesar 1,107%. Kata Kunci: daun dadap serep (Erythrina lithosperma Miq.), larva Aedes aegypti [L.], mortalitas ABSTRACT Amalina Elvira Anggraini, G0014023, 2017. The Effect of Ethanol Extract of Dadap Serep (Erythrina lithosperma Miq.) to Mortality of Aedes aegypti [L.] Larvae. Thesis. Faculty of Medicine, Sebelas Maret University, Surakarta. Background: Many ways have been done to kill Aedes aegypti [L.], species that caused dengue fever, chikungunya, and zika, one of them was temephos 1%. Unfortunately, some studies mentioned that the use of tempehos 1% have made resisteance in some cities in Indonesia, especially Central Java. Thus, it was really needed to do a research aimed to find natural larvacide made from natural resources, such as dadap serep (Eryhtrina lithosperma Miq.) that contains Flavonoid, Saponin, and Tannin inside. This research aimed to know whether the ethanol extract of dadap serep (Erythrina lithsperma Miq.) had mortality effect to Aedes Aegypti [L.] larvae. Methods: This research used a laboratory quasi experimental design with post test only controlled group design. The subject of this research was Aedes aegypti [L.] that was divided into 6 groups, each group contained 25 larvae and repeated 4 times. For the negative control group we used 100 ml of aquadest only. The other five groups contained different number of ethanol extract of dadap serep. There are 0,3%; 0,5%; 0,7%; 0,9%; and 1,1%. The observation was done after 24 hours and the number of dead larvae was counted. Data analyzed by Linear Regression and Probit Regression. Result: Linear Regression test showed that increasing of the ethanol extract of Dadap Serep affected to the increasing of Aedes aegypti [L.] mortality based on Y=0,024 + 0,956X formula. The R correlation was 0,968 and R2 score was 0,968 meant that percentage of ethanol extract of dadap serep (Erythrina lithosperma Miq.) to kill larvae was 96,8% and the rest 3,2% was affected by other variables. Probit Regression test showed LC50 was 0,492% and LC99 was 1,107%. Conclusion: Ethanol extract of dadap serep (Erythrina lithosperma Miq.) affect to the mortality of Aedes aegypti [L.] paralleled to the increasing of ethanol extract. LC50 is 0,492% and the LC99 is 1,107%. Keywords: ethanol extract of dadap serep (Erythrina lithosperma Miq.), Aedes aegypti [L.] larvae, mortality.

    Item Type: Thesis (Other)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Fakultas Kedokteran > Pendidikan Kedokteran
    Depositing User: Mujahidah Showafah
    Date Deposited: 28 Mar 2018 17:06
    Last Modified: 28 Mar 2018 17:06
    URI: https://eprints.uns.ac.id/id/eprint/40371

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