PENGARUH PEMBERIAN EKSTRAK AIR KELOPAK BUNGA ROSELA (Hibiscus sabdariffa L.) TERHADAP KADAR KOLESTEROL TOTAL DARAH DAN BERAT BADAN TIKUS PUTIH (Rattus norvegicus)

MARSALINA, MEISA (2010) PENGARUH PEMBERIAN EKSTRAK AIR KELOPAK BUNGA ROSELA (Hibiscus sabdariffa L.) TERHADAP KADAR KOLESTEROL TOTAL DARAH DAN BERAT BADAN TIKUS PUTIH (Rattus norvegicus). Other thesis, Universitas Sebelas Maret.

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    Abstract

    Meisa Marsalina, G0006116, 2010. THE INFLUENCE OF AQUEOUS EXTRACT OF ROSELLE (Hibiscus sabdariffa L.) CALYX ON BLOOD CHOLESTEROL LEVEL AND BODY WEIGHT IN RATS, Medical Faculty, Sebelas Maret University, Surakarta. Objective : This study aimed at investigating the influence of aqueous extract of roselle calyx on blood cholesterol level and body weight in rats. Methods : This experimental research was arranged as a pre and post-test controlled group design. Thirty Sprague Dawley rats, with 3 months of ages and 250g in average weight were used as an animal model. Those rats were grouped equally into five, namely negative control (aquadest), positive control (0,26mg lovastatin/200g body weight of rats/2ml), first dose of aqueous extract of roselle calyx (65mg/200g/2ml), second dose of aqueous extract of roselle calyx (130mg/200g/2ml), third dose of aqueous extract of roselle calyx (195mg/200g/2ml). The measurement of rats blood cholesterol level was conducted before and after treatment, while rats body weight was measured once a week. The result of this study was analyzed using one-way ANOVA statistical test. Results : The one-way ANOVA statistical test showed no significant differences on reducing blood cholesterol level with p=0,327 (p>0,05) and body weight in rats with p=0,154, p=0,214, p=0,938 (p>0,05). Conclusion : This study concludes that aqueous extract of roselle calyx have no influence on lowering blood cholesterol level and body wieght in rats. Keywords: aqueous extract of roselle calyx; blood cholesterol level; rats body weight.

    Item Type: Thesis (Other)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Fakultas Kedokteran > Pendidikan Kedokteran
    Depositing User: Isro'iyatul Mubarokah
    Date Deposited: 14 Jul 2013 18:21
    Last Modified: 14 Jul 2013 18:21
    URI: https://eprints.uns.ac.id/id/eprint/3811

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