Pengaruh Hemodialisis terhadap Terjadinya Trombositopenia pada Pasien Penyakit Ginjal Kronik di RSUD Dr. Moewardi

AGNES S, ELISABETH (2017) Pengaruh Hemodialisis terhadap Terjadinya Trombositopenia pada Pasien Penyakit Ginjal Kronik di RSUD Dr. Moewardi. Other thesis, Universitas Sebelas Maret.

[img] PDF - Published Version
Download (227Kb)

    Abstract

    ABSTRACT Introduction: Thrombocytopenia can happen in patients with Chronic Kidney Disease (CKD). Uremic syndrome on CKD causes 10% of patients with CKD without hemodialysis have thrombocytopenia. The occurence of thrombocytopenia increases to 31% in patients with CKD who undergoing hemodialysis. It happens because given heparin for preventing blood clotting occurs during hemodialysis. The effect of heparin is reducing function and platelet count. This research aims to determine the effect of hemodialysis on the occurrence of thrombocytopenia in patients with chronic kidney at RSUD Dr. Moewardi. Methods: This study was an analytical observational study using cohort retrospective method. This research was conducted in hemodialysis department RSUD Dr. Moewardi on October 2th – November 9th 2016. Subjects of this study were patients with CKD at RSUD Dr. Moewardi matched with inclusion and exclusion criteria. The sampling was done by the fixed exposure sampling and simple random sampling. Total samples were 100 patients who categoried into 3 groups by frequency of hemodialysis. The data obtained were processed using SPSS for windows 22.0 and analyzed using chi-square test Results:. Patients with CKD who undergoing hemodialysis 1x / week have risk of thrombocytopenia 1.5x more than patients without hemodialysis (OR = 1,47 ; CI 95% 0,37-5,78; p = 0,583)), while patients with CKD undergoing hemodialysis 2x / week have risk of thrombocytopenia 7,3x risk more than patients without hemodialysis (OR = 7,33 ; CI 95% 2,33-23,12; p < 0,001). Conclusions: There is an effect of hemodialysis on the occurrence of thrombocytopenia in patients with CKD at RSUD Dr. Moewardi. Patients with higher frequency of hemodialyis have more risk of thrombocytopenia Keywords: Chronic Kidney Disease, Hemodialysis, Frequency, Thrombocytopenia

    Item Type: Thesis (Other)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Fakultas Kedokteran
    Depositing User: Figur Hisnu Aslam
    Date Deposited: 30 Mar 2017 14:00
    Last Modified: 30 Mar 2017 14:00
    URI: https://eprints.uns.ac.id/id/eprint/32869

    Actions (login required)

    View Item