Hubungan Body Mass Index dan Asupan Vitamin D dengan Serum 25-Hydroxyvitamin D Pasien Kanker Payudara

YUNI DAMAYANT, AMILIA (2016) Hubungan Body Mass Index dan Asupan Vitamin D dengan Serum 25-Hydroxyvitamin D Pasien Kanker Payudara. Other thesis, Universitas Sebelas Maret.

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    Amilia Yuni Damayanti, S531408016. 2016. THE RELATHIONSHIP BETWEEN BODY MASS INDEX AND VITAMIN D INTAKE WITH SERUM 25-HYDROXYVITAMIN D IN BREAST CANCER. THESIS. Supervisor I : Brian Wasita,dr.,Sp.PA.,PhD, Supervisor II : Tonang Dwi Ardyanto,dr.,Sp.PK.,Ph.D, Magister of Nutrition, Postgraduate Program, Sebelas Maret University, Surakarta. ABSTRACT Background: Breast cancer is the most common malignancy which is found in women in the world. Vitamin D helps control the majority of gene expression in female reproductive tissues. Body Mass Index (BMI) influences the bioavailability of vitamin D. Diet is one of the main sources of vitamin D and it is directly converted into 25-hydroxyvitamin D [25 (OH) D] in the liver. This study aimed to analyze the relationship between BMI and vitamin D intake and 25 (OH)Dserum in patients with breast cancer. Methods: Analytic observationalwith cross sectional design was used in this study. A total of 37 patients with breast cancer who visited Dr. Moewardi Hospital at Surakarta was selected as research subjects using a purposive sampling technique. BMI data was obtained by measuring body weight and height. Vitamin D intakewas determined using 1x24-hour food recall and semi-quantitative food frequency questionnaire. While 25 (OH)D serum was measured using enzyme-linked immunoabsorbent assay. Data analysis used Spearman correlation test. Results: The average of BMI, vitamin D intake and 25(OH)D serum of breast cancer patients was 21.96±3.63 kg/m², 3.50±3.30 µg/day and 16.01±14.67 ng/mL respectively. Most patients with breast cancer had less intake of vitamin D and deficiency of 25(OH)D serum.There was a weak relationship between BMI (r=0188, p=0.266) and vitamin D (r=0.113, p=0.507) and 25 (OH)Dserumin patients with breast cancer. Conclusion: BMI and vitamin D intake weakly correlatewith 25(OH)D serum in patients with breast cancer.Therefore BMI, vitamin D intake and serum 25 (OH) D levels need to be controlled. Need further study on the effect of chemotherapy regimens on metabolism of vitamin D. Key word: BMI, Vitamin D Intake, 25(OH)DSerum, Breast Cancer.

    Item Type: Thesis (Other)
    Subjects: R Medicine > RZ Other systems of medicine
    Divisions: Pasca Sarjana
    Pasca Sarjana > Magister > Ilmu Gizi
    Depositing User: Rina Dwi Setianingrum
    Date Deposited: 26 Nov 2016 13:41
    Last Modified: 26 Nov 2016 13:41

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