UJI AKTIVITAS ANTIINFLASI EKSTRAK ETANOL DAUN COCOR BEBEK (Kalanchoe pinnata (lam.) pers.) TERHADAP JUMLAH LEUKOSIT TOTAL DAN EDEMA PADA RADANG AKUT TELAPAK KAKI TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI KARAGENAN

Allaeinni, Reguird (2015) UJI AKTIVITAS ANTIINFLASI EKSTRAK ETANOL DAUN COCOR BEBEK (Kalanchoe pinnata (lam.) pers.) TERHADAP JUMLAH LEUKOSIT TOTAL DAN EDEMA PADA RADANG AKUT TELAPAK KAKI TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI KARAGENAN. Other thesis, Universitas Sebelas Maret.

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    Abstract

    Inflammatory as one of immunologic response often accompanied with edema which has fairly high incidence rate. Life plant (Kalanchoe pinnata (Lam.)Pers.) is a plant that empirically used as traditional medicine in many countries in Asia and Africa, one of them as anti-inflammatory. As of today, research about the benefits of life plant in medical field is growing, but that is not the case inIndonesia. This research intends to know the anti-inflammatory activity and optimum dosage from the ethanol extract of the life plant against edema and also total count of leukocyte in male albino rat foot that has been induced with 1% of carrageenan. Anti-inflammatory activity decided by calculate the reduction in edema volume using plethysmometer and the total count of leukocytes using booth number. Ethanol extract from life plant that acquired using maceration method given orally to the rats. Doses used are 300 mg/kg weight albino rat and 600 mg/kg weight albino rat. Test result then statistically analyzed using one-way ANOVA with 95% level of confidence. The result showed that ethanol extract from life plant administration affects the edema volume on the albino rat’s foot without significantly affecting the number of leukocytes. 300 mg/kg weight is more optimal in preventing or healing edema with the percentage of inflammation reduction of 35.02% and 69.75%. Keywords: antiinflammatory, edema, leukocyte, ethanolic extract,life plant (Kalanchoe pinnata(Lam.) Pers.)

    Item Type: Thesis (Other)
    Subjects: Q Science > QK Botany
    Q Science > QL Zoology
    Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam > Biologi
    Depositing User: Minardi Aris
    Date Deposited: 25 Sep 2015 00:22
    Last Modified: 25 Sep 2015 00:22
    URI: https://eprints.uns.ac.id/id/eprint/19504

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