HUBUNGAN ANTARA KADAR HEMATOKRIT DENGAN DERAJAT KEPARAHAN STROKE ISKEMIK FASE AKUT PADA PASIEN DI UNIT PENYAKIT SARAF RSUD DR. MOEWARDI

Hidayat, Agung Wahyu (2013) HUBUNGAN ANTARA KADAR HEMATOKRIT DENGAN DERAJAT KEPARAHAN STROKE ISKEMIK FASE AKUT PADA PASIEN DI UNIT PENYAKIT SARAF RSUD DR. MOEWARDI. Other thesis, UNIVERSITAS SEBELAS MARET.

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    Abstract

    Agung Wahyu Hidayat, G0010009, 2013. Hubungan antara Kadar Hematokrit dengan Derajat Keparahan Stroke Iskemik Fase Akut pada Pasien di Unit Penyakit Saraf RSUD Dr. Moewardi. Skripsi. Fakultas Kedokteran Universitas Sebelas Maret, Surakarta. Latar Belakang: Stroke merupakan penyebab utama kecacatan dan ketiga kematian di dunia, juga penyebab utama gangguan fungsional pada pasien. Peningkatan kadar hematokrit merupakan salah satu faktor risiko terjadinya stroke iskemik, dengan peningkatan viskositas dan penurunan persuasi darah ke otak. National Institute of Health Stroke Scale (NIHSS) merupakan satu parameter yang digunakan untuk mengukur keparahan dari stroke iskemik akut. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar hematokrit dengan derajat keparahan stroke iskemik akut pada pasien di Unit Penyakit Saraf RSUD Dr. Moewardi. Metode Penelitian: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Sebanyak 44 subjek penelitian yang dipilih dengan purposive sampling adalah pasien stroke iskemik di Ruang Rawat Inap Anggrek II RSUD Dr. Moewardi. Pengambilan data dilakukan dengan wawancara langsung dan pemeriksaan menggunakan skor NIHSS kepada pasien. Data hasil penelitian dianalisis menggunakan model regresi logistik ganda dan diolah dengan Statistical Product and Service Solution (SPSS) 17.00 for Windows. Hasil Penelitian: Penelitian ini menunjukkan nilai korelasi Spearman r = 0,408; p < 0,009 yang berarti terdapat korelasi positif yang secara statistik bermakna antara kadar hematokrit dan derajat keparahan stroke iskemik fase akut dengan kekuatan korelasi sedang. Uji regresi logistik ganda menunjukkan hasil OR = 8,086; CI 95% 1,108 – 59,005; dan p = 0,039. Hasil ini sudah mengontrol variabel perancu yaitu merokok dan kadar gula darah sewaktu. Pasien yang memiliki kadar hematokrit tinggi memiliki risiko derajat keparahan stroke iskemik 8,086 lebih berat dibandingkan dengan yang normal. Simpulan Penelitian: Terdapat hubungan sedang antara kadar hematokrit dengan derajat keparahan stroke iskemik fase akut pada pasien di Unit Penyakit Saraf RSUD Dr. Moewardi Kata Kunci: kadar hematokrit, derajat keparahan stroke iskemik akut, NIHSS Agung Wahyu Hidayat, G0010009, 2013. The Correlation between Hematocrit Levels and Severity of Acute Ischemic Stroke in Patient of Neurological Disease Unit at Dr. Moewardi Hospital . Mini Thesis. Faculty of Medicine, University of Sebelas Maret Surakarta. Background: Stroke is the main cause of morbidities and the third leading cause of death in the world, also promote the functional disorder of the patient. The increase of hematocrit level is one of risk factor the occurrence of ischemic stroke, by increasing the viscosity and decreasing blood perfusion to the brain. National Institute of Health Stroke Scale (NIHSS) is a parameter used to measure the severity of acute ischemic stroke. This research proposed to know the correlation between hematocrit level and severity of acute ischemic stroke in patient of neurological disease unit at Dr. Moewardi Hospital. Methods: This study was observational cross sectional analytic approach. A total of 44 subjects were selected by purposive sampling, they were ischemic stroke patients in the room Anggrek II Dr. Moewardi Hospital. Data was collected by direct interview and examination of the patient by using NIHSS score. Data was analyzed by using multiple logistic regression models and processed with Statistical Product and Service Solutions (SPSS) 17.00 for Windows. Results: This study shows the value of Spearman correlation r = 0,408; p < 0,009 which means there is a positive correlation was statistically significant between hematocrit levels and the degree of severity of ischemic stroke in acute ischemic stroke patient with a moderate correlation strength. Multiple logistic regression shows the result of OR = 8,086; CI 95% 1,108 – 59,005; and p = 0,039. These results had controlled the confounding factor, e.g smoking, and blood sugar. The patients whose high hematocrit level are have risk severity of acute ischemic stroke 8,086 greater than normal. Conclusions: There is a moderate correlation between hematocrit levels and the degree of severity of acute ischemic stroke in patient of neurological disease unit at Dr. Moewardi Hospital. Keywords: hematocrit levels, severity of acute ischemic stroke, NIHSS

    Item Type: Thesis (Other)
    Subjects: R Medicine > RA Public aspects of medicine
    Divisions: Fakultas Kedokteran > Pendidikan Kedokteran
    Depositing User: Satria Nur Fauzi
    Date Deposited: 06 May 2014 20:24
    Last Modified: 06 May 2014 20:24
    URI: https://eprints.uns.ac.id/id/eprint/15187

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