FORMULASI DAN STUDI EFEKTIVITAS KRIM EKSTRAK ETANOL DAUN UBI JALAR (Ipomoeae batatas L.) UNTUK PENGOBATAN LUKA BAKAR PADA MENCIT PUTIH (Musmusculus albinus)

Aditama, Tias (2013) FORMULASI DAN STUDI EFEKTIVITAS KRIM EKSTRAK ETANOL DAUN UBI JALAR (Ipomoeae batatas L.) UNTUK PENGOBATAN LUKA BAKAR PADA MENCIT PUTIH (Musmusculus albinus). Other thesis, Universitas Sebelas Maret.

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    Abstract

    Sweet potato leaves (Ipomoeae batatas L.) contain saponins and flavonoids substances that can be used to fastered the healing of burns. Flavonoids has antiseptic capability, while saponins was one of the compound which triggering forming of collagen and as a cleanser so that can to fastered the healing of burns. This research is aimed to determine the effect of ethanol extract of sweet potato leaves on cream stability both physically and chemically, and the effectiveness of the healing of burns. Research has been done by formulating cream type M/A with extract concentration 0%, 3%, 6% and 9%. Cream is tested with organoleptic, homogenity, viscosity, pH, and the effectiveness of the healing of burns. The effectiveness of burns is tested with 15 mices as experimental animal were burned with diameter of 1 cm. The data that use obtained were compared with there ference standard and analyzed using statistic trough two way ANOVA test with 95% confidence level. For effectiveness was analyzed using linear regression test. The results showed that all the creams stable in organoleptic as pects and homogeneity. The addition of the extract gave effect to the viscosity and pH of the cream. Based on linear regression test the effect of additioned sweet potato leaf extract for the increasing the healing of burns percent is 92,9%. Cream with 9% ethanol extract of sweet potato leaves has gave an optimum effect up to 71,66% which is not yet equivalent to the trademark Z in the market that is 81,66%.

    Item Type: Thesis (Other)
    Subjects: Q Science > QH Natural history > QH301 Biology
    Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam
    Depositing User: Vignasari Kokasih
    Date Deposited: 26 Apr 2014 18:21
    Last Modified: 26 Apr 2014 18:21
    URI: https://eprints.uns.ac.id/id/eprint/13552

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