Perbedaan Efek Ekstrak Etanol Stevia Dibandingkan Madu Terhadap Perubahan Glukosa Darah Tikus Wistar Model Diabetik

Fatimah, siti and Kisrini , and Febrinasari, Ratih Puspita (2012) Perbedaan Efek Ekstrak Etanol Stevia Dibandingkan Madu Terhadap Perubahan Glukosa Darah Tikus Wistar Model Diabetik. -.

[img]
Preview
PDF - Published Version
Download (98Kb) | Preview

    Abstract

    Background:Stevia’s leaf contains steviol, stevioside and rebaudioside which have effect to increase secretion insulin. Honey, natural sweetener contains several antioxidant such as propolis, flavonoid and vitamin. It will eliminate free radicals and indirectly improve pankreas glands cells to produce insulin. This research was aimed to know the difference effect of stevia’s ethanol extract comparedto honey on changing of blood glucoselevel on diabetic model Wistar rats. Methods:This was experimental research with pre and post test controlled group design. Samples were 32 male rats, Wistar Strain, 6-8 weeks and + 200 gweight. Sampling technique used in this research was incidental sampling. Samples were divided into 4 groups: negative control group (aquadest), positive control (glibenclamide dose 0.09 mg/200 g body weight), treatment group 1 (stevia’s ethanol extract dose 20 mg/200 g body weight), treatment group 2 (honey dose 2 ml/200 g body weight). Data were analyze using Saphiro-Wilk’s test of normality and Friedmann test (α = 0.05) and Post Hoc Multiple Comparison (Wilcoxon) (α = 0.05) using SPSS 17 for Windows. Results:There was a significant difference (p = 0.002) on the Wistar’s blood glucose level which was given stevia’s ethanol extract or honey. Stevia’s ethanol extract effect more on decreasing the blood glucose than honey. But, the both of them are able to decrease the Wistar’s blood glucose on diabetic model Conclusions:Stevia’s ethanol extract has the effect of decreasing blood glucose level on diabetic model Wistar rats better than honey.

    Item Type: Article
    Subjects: Q Science > Q Science (General)
    Divisions: Lembaga Penelitian dan Pengabdian Kepada Masyarakat - LPPM
    Depositing User: Dyah Pratiwi
    Date Deposited: 20 Apr 2014 18:48
    Last Modified: 20 Apr 2014 18:48
    URI: https://eprints.uns.ac.id/id/eprint/12614

    Actions (login required)

    View Item