HUBUNGAN ANTARA FATTY LIVER DENGAN HIPERTENSI SISTEMIK DI RSUD DR MOEWARDI DI SURAKARTA

Belawati, Yeny Ristaning (2012) HUBUNGAN ANTARA FATTY LIVER DENGAN HIPERTENSI SISTEMIK DI RSUD DR MOEWARDI DI SURAKARTA. Other thesis, Universitas Sebelas Maret.

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    Abstract

    ABSTRAK Yeny Ristaning Belawati, G0009214, 2012. Hubungan antara Fatty Liver dengan Hipertensi Sistemik di RSUD Dr. Moewardi di Surakarta. Skripsi. Fakultas Kedokteran Universitas Sebelas Maret, Surakarta. Latar Belakang: Fatty liver merupakan proses akumulasi lemak pada hati mulai dari steatosis sederhana sampai nonalcoholic steatohepatitis (NASH) dan sirosis. Steastosis sederhana merupakan bentuk paling umum dan jinak, sebaliknya NASH merupakan kondisi yang berpotensi serius. Hal tersebut bisa dilihat dari hasil pemeriksaan laboratorium darah, seperti peningkatan kadar ALT, GGT, alkalin fosfatase, ferritin dan gangguan tes fungsi hepar yang lain. Hipertensi merupakan salah satu kondisi gangguan metabolik dan melalui mekanisme yang belum diketahui terdapat dugaan ada hubugan antara fatty liver dengan hipertensi sistemik. Metode Penelitian: Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Sampel dipilih dengan teknik purposive sampling. Jumlah sampel yaitu 20 pasien fatty liver dan 20 pasien non-fatty liver. Lokasi penelitian di Instalasi Radiologi RSUD Dr. Moewardi di Surakarta. Waktu penelitian pada bulan Juni 2012. Pengambilan data dilakukan dengan melihat hasil pemeriksaan USG abdomen fokus hepar dan pengukuran tekanan darah menggunakan tensimeter yang dilakukan oleh peneliti. Data hasil penelitian dianalisis menggunakan uji Chi Square untuk melihat hubungan antara kedua variabel dan menggunakan uji Odds Ratio untuk melihat kekuatan hubungan antarvariabel. Data diolah dengan Statistical Product and Service Solution (SPSS) 17.00 for Windows. Hasil Penelitian: Berdasarkan penghitungan statistik, menunjukkan hubungan secara signifikan antara fatty liver dengan hipertensi sistemik (p < 0,05). Dari penghitungan Odds Ratio dapat diketahui pasien fatty liver memiliki risiko untuk mengalami hipertensi sistemik 7 kali lebih besar daripada pasien non-fatty liver (OR = 7). Simpulan tersebut dibuat setelah mengontrol umur, namun belum mengontrol predisposisi genetik, intake natrium, dan pengaruh obesitas. Simpulan Penelitian: Terdapat hubungan antara fatty liver dengan hipertensi sistemik di RSUD Dr. Moewardi di Surakarta, pasien fatty liver memiliki risiko mengalami hipertensi sistemik sebanyak 7 kali lebih besar disbanding pasien nonfatty liver Kata kunci : Fatty Liver, Hipertensi Sistemik, USG Abdomen ABSTRACT Yeny Ristaning Belawati, G0009214, 2012. The Relationship between Fatty Liver and Systemic Hypertension in RSUD Dr. Moewardi at Surakarta. Thesis. Medical Faculty of Sebelas Maret University, Surakarta. Background: Fatty liver is the accumulation of fat in the liver ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Steastosis simplest and most common form of benign, whereas NASH is a potentially serious condition. Patients fatty liver is often associated with metabolic disorders. It can be seen from the results of laboratory tests of blood, such as elevated levels of ALT, GGT, alkaline phosphatase, ferritin, and impaired liver function test to another. Hypertension is one of the conditions of metabolic disorders, and through an unknown mechanism allegation contained no relationship between fatty liver with systemic hypertension Method: This study was an analytical observational research with cross-sectional approach. The sample was taken using purposive sampling technique. The sample consisted of 20 fatty liver’s patients and 20 non-fatty liver’s patients. The research was taken place in Radiology Installation of Dr. Moewardi Local General Hospital. The research was conducted at June 2012. The data was collected by viewing the result of USG abdomen focus hepar examination and measuring patient’s blood pressure by researcher. The data of research was analyzed using Chi Square test and Odds Ratio. Data processed using Statistical Product and Service Solution (SPSS) 17.00 for Windows. Result: From calculation of statistic there was a significant correlation between fatty liver and hypertension systemic in RSUD Dr. Moewardi at Surakarta (p < 0,05). From the calculation if Odds Ratio, the fatty liver patients had risk of hypertension systemic 7 times higher than the non-fatty liver patients had (OR = 7) The conclusion was drawn after controlling age, but not about the gen predisposition, natrium intake and obesity. Conclusion: There was a significant relationship between fatty liver and hypertension systemic in RSUD Dr. Moewardi Surakarta, fatty liver patients have a risk of systemic hypertension as much as 7 times greater than the non-fatty liver patients Keywords: Fatty Liver, Hypertension Systemic, USG Abdomen

    Item Type: Thesis (Other)
    Subjects: R Medicine > R Medicine (General)
    Divisions: Fakultas Kedokteran > Pendidikan Kedokteran
    Depositing User: Nurrahma Restia
    Date Deposited: 03 May 2014 18:01
    Last Modified: 03 May 2014 18:01
    URI: https://eprints.uns.ac.id/id/eprint/11111

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