HUBUNGAN PEMBERIAN EKSTRAK DAUN SENDOK (Plantago major L.) TERHADAP HITUNG EOSINOFIL DARAH TEPI PADA MENCIT Balb/C MODEL ASMA ALERGI

PURNANINGRUM, SISILIA FITRIA (2010) HUBUNGAN PEMBERIAN EKSTRAK DAUN SENDOK (Plantago major L.) TERHADAP HITUNG EOSINOFIL DARAH TEPI PADA MENCIT Balb/C MODEL ASMA ALERGI. Other thesis, Universitas Sebelas Maret.

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    Abstract

    Objective: Tounderstandrelationship between daun sendok extract with eosinophyll peripheral blood count on Balb/C mice asthma allergic model. Methods:Experimental laboratoric with post-test only control group design using 40 Balb/C male mice, divided into five groups. Sample was sensitized by 0,15 cc ovalbumin (OVA) inAl(OH)3 on day-0 and day-10 intraperitoneally, continued in day-15, 17, 19, 21 and23with OVA aerosolly in 20 minutes, also continued in day-16, 18, 20, 22 and24with cigaret aerosolly. In day-25, blood sample was collected from tail , the eosinophyll count was conducted using cell counter after staining a blood smear using Wright Giemsain 5 view fields. Data analyzed using SPSSfor Window Release 16.0. Statistically significant p<0,05. Results: Eosinophyllperipheral blood count in control group 3,25 ± 1,83 cells, asthma allergic 5,5 ± 3,74 cells, anti-histamine 2,25 ± 1,98 cells, 1 mg/mice daun sendok extract 5,25 ± 4,2 cells, and 2 mg/mice daun sendok extract 3 ± 2,56 cells. There is no significant difference between control group with daun sendok 1 mg/mice group in eosinophyll count (p=0,457), same as in eosinophyll count between daun sendok 1 mg/mice group with anti-histamine (p=0,200) . Conclusion:There is no corellation between daun sendok (Plantago major L.) extract with eosinophyll peripheral blood count on Balb/C mice asthma allergic model (p>0,05). Keyword: asthma allergic, daun sendok, eosinophyll

    Item Type: Thesis (Other)
    Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
    Divisions: UNSPECIFIED
    Depositing User: Lia Primadani
    Date Deposited: 23 Aug 2013 05:03
    Last Modified: 23 Aug 2013 05:03
    URI: https://eprints.uns.ac.id/id/eprint/10414

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